Endocrine Abstracts

The study evaluates the expression of same immunohistochemical (IHC) markers (Ki-67, PCNA, CK-19, HBME-1 and Galectin 3, in the diagnosis of differentiated thyroid carcinomas.Material and methods: The study group comprised 57 patients with thyroid tumors; aged 17–71 years (mean age 48.96 years). All cases were evaluated before surgical treatment by means of clinical examination, thyroid ultrasonography and fine needle aspiration biopsy (FNAB).<p...

Introduction: Primary hyperparathyroidism (PHP) affects predominantly the adult age (incidence 1/10 000) and it is unusual.The aim of the study: Is to present a rare pathology in a child, which implied interdisciplinary collaboration.Material and method: We present a teenager girl of 16 years old, diagnosed with osteomalacia after a thoracic and pelvis trauma, based on knee and pelvis radiographs (diffuse bone demineralization, tra...

Graves’ orbitopathy (GO) represents ophthalmic symptoms that affect, usually, patients with Graves’ disease. Rarely, it can occur in subjects without thyroid dysfunction or with hypothyroidism (2–5% of the cases).In this report we present a rare case with unilateral GO and initial euthyroidism, which progressed to hypothyroidism, due to an autoimmune atrophic thyroiditis.A 39-year-old woman, long-term smoker, was ref...

IntroductionThe global pandemic caused by the SarsCov2 virus has brought great challenges to the medical system, the management of some cases, especially for those belonging to risk categories, such as pregnant women, being often difficult in this context. Telemedicine has been used frequently during this period, facilitating reducing patient’s risk for exposure to COVID-19, providing continuous support, and coordinating the necessary services to pr...

Introduction: Somatostatin analogues (SSA) have been used as first line treatment to control the symtoms in hormonally active neuroendocrine tumors (NET), for over three decades. Primary hepatic neuroendocrine tumors (PHNETs) are rare neoplasms. Despite increased incidence of PHNETs over time, these tumors remain a rarity. According to the previously reported cases, primary neuroendocrine carcinoma of the liver is usually multicentric, often mimicking liver metastases. The dem...

Background: Postpartum hypopituitarism, known as Sheehan’s syndrome, occurs during a complicated childbirth, due to severe hemorrhage and hpovolemic shock that lead to ischemic necrosis of the pituitary gland.The aim of the study is to point out the clinical features in postpartum pituitary necrosis, so that the disease could be recognize rapidly, to present a laboratory work-up for a postive diagnosis, and also to describe the com...

The cardiovascular system (CVS) is one of the major targets of thyroid hormone action.The thyroid function has a direct effect on heart rate, cardiac output and systemic vascular resistance.The prevalence of hypothyroidism in the general population is high, particularly in females (9–15%). Overt hypothyroidism is associated with severe cardiovascular manifestations including reduced intravascular volume, increased systemic vas...

Sleep apnea syndrome is highly prevalent in acromegaly and only partially reversible after biochemical control of the disease. Consequences of SAS are serious and are associated with increased morbidity and mortality.The present study evaluates clinical aspects in acromegalic patients with sleep apnea syndrome (SAS), diagnosed and followed-up in the Clinic of Endocrinology, Timisoara, in the period 2007–2010. All the cases were confirmed and investi...

The aim of the study: Acromegaly is associated with respiratory and cardiovascular morbidities and high mortality rate. The present study evaluates clinical aspects in acromegalic and obese patients with sleep apnea syndrome (SAS).Material and method: The patients were diagnosed and followed-up in the Clinic of Endocrinology, Timisoara, in the period 2006–2009. All the cases were confirmed and investigated as present guidelines recommend. The polyso...

This study represents a complex evaluation of a group of 26 cases with thyroid nodular disease (TND), using different diagnostic methods. Clinically and by means of ultrasonography, 12 patients were suspected of malignancy. Fine-needle aspiration biopsy (FNAB) detected mainly suspicious (12 cases) and malignant smears (5 cases). The microscopic examination of surgical specimens established the following diagnosis: follicular adenoma – FA (4 cases), papillary hyperplasia &...